2. Signaling Pathways
  3. Immunology/Inflammation
  4. Interleukin Related
  5. IL-5 Isoform
  6. IL-5 Activator

IL-5 Activator

IL-5 Activators (3):

Cat. No. Product Name Effect Purity
  • HY-180898
    AHL-7160
    		Activator
    AHL-7160 is a covalent DGKα inhibitor that possesses dual functions of enzyme activity inhibition (IC₅₀ ≈ 12 nM) and molecular gel-mediated degradation. AHL-7160 can rapidly recruit endogenous DGKα to the cell membrane (EC₅₀ = 39 nM), and this effect has isozyme selectivity. AHL-7160 can stereospecifically block phosphatidylcholine acid (PA) production mediated by DGKα (IC₅₀ = 340 nM). AHL-7160 enhances T cell activation and promotes anti-tumor immune responses. AHL-7160 can be used for research on immunotherapy.
  • HY-NP159
    House Dust Mite Extract, from D.farinae
    		Activator
    House Dust Mite Extract, from D.farinae is a house dust mite allergen extract derived from Dermatophagoides farinae. House Dust Mite Extract, from D.farinae significantly increases the levels of cytokines (IL-4, IL-5, IL-6) in bronchoalveolar lavage fluid. House Dust Mite Extract, from D.farinae upregulates the overexpression of MUC5AC. House Dust Mite Extract, from D.farinae induces allergic asthma and pulmonary inflammation.
  • HY-NP159A
    House Dust Mite Extract, from D.pteronyssinus
    		Activator
    House Dust Mite Extract, from D. pteronyssinus is a house dust mite allergenic extract derived from Dermatophagoides pteronyssinus. House Dust Mite Extract, from D. pteronyssinus increases serum IgE, IgG1 and IgG2a levels, and elevates the levels of Interleukins 4, 5, 6, 10, 13 and 17. House Dust Mite Extract, from D. pteronyssinus induces significant asthmatic pathological changes. House Dust Mite Extract, from D. pteronyssinus can be used in studies related to asthma and allergic conjunctivitis.